What is Botulinum toxin?
BOTOX Cosmetic and Dysport are the purified form of toxin (botulinum toxin-a) derived from Chlostridium botulinum, the bacterium that is directly associated with botulism. It is used in treating age lines or wrinkles (cosmetic), as well as other health problems such as dystonia, hyperhidrosis and migraine headaches (medical).
Are Botox Cosmetic and Dysport approved by the FDA?
Yes, Botox is approved by the FDA as a cosmetic and medical treatment.
Botox was first approved by the FDA in 1989 as a medical treatment for 2 eye disorders namely Blepharospasm (uncontrollable blinking) and Strabismus (misaligned eyes).
In 2000, the FDA approved Botox to treat cervical dystonia, a neurological disorder that causes severe shoulder and neck muscles contraction.
Botox was approved by the FDA as a cosmetic treatment in April of 2002.
In 2004, the FDA approved Botox as a treatment for axillary hyperhidrosis for patients who do not respond positively to topical prescription drugs.
In 2009, the FDA approved Dysport for treatment of glabellar (frown) lines.
What can botulinum toxin be used for?
Botulinum toxin can be used to treat facial wrinkles caused by muscle activity. Most commonly, it is used for the frown lines between the eyebrows, but can also be used to treat crowsfeet and horizontal forehead lines. Botulinum toxin can also be used on bunny lines on the nose, vertical lip lines (smokers lines), chin dimpling, and the vertical neck bands as well. It can also be used to shape or lift the eyebrows and raise the corners of the mouth.
Non-cosmetic use of Botox include treatment of headaches and localized excessive sweating, especially of the armpits.
What are the side effects and risks to botulinum toxin treatment?
Side effects from botulinum toxin treatments are infrequent and generally mild and temporary. Treatment side effect can include bruising at the injection site. Some people may have a mild headache after injection.
The most common significant complication, which is rare, is drooping of the eyelids or eyebrows. This is temporary.
Who cannot have botulinum toxin injections?
Botulinum toxin injections should not be used during pregnancy or while breast feeding. It is also contraindicated in persons with certain neuromuscular diseases such as Myasthenia Gravis.
Caution is advised in persons taking the following medications:
- Certain antibiotics (may increase the effect of botulinum toxin)
- Blood thinning agents (may result in bruising)